iPfam is a resource that describes physical interactions between protein families (currently just Pfam) that have a known structure in the Protein DataBank (PDB). When two or more domains occur within a single structure, the domains are analysed to see if they form an interaction. If the domains are close enough to form an interaction, the bonds that play a role in that interaction are determined. The structures are also analysed to identify interactions between the domain(s) and any small molecule ligands that are co-crystalized with the structure.
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Howard Hughes Medical Institute